Title : BRD4 PROTAC degrader ARV-825 inhibits T-cell acute lymphoblastic leukemia by targeting 'Undruggable' Myc-pathway genes.

Pub. Date : 2021 Apr 22

PMID : 33888130






1 Functional Relationships(s)
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1 In the T-ALL xenograft model, ARV-825 significantly reduced tumor growth and led to the dysregulation of Ki67 and cleaved caspase 3. omega-N-Allylarginine caspase 3 Homo sapiens