Title : Divergent Regulation of Alveolar Type 2 Cell and Fibroblast Apoptosis by Plasminogen Activator Inhibitor 1 in Lung Fibrosis.

Pub. Date : 2021 Jul

PMID : 33887217






1 Functional Relationships(s)
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1 In vivo studies further show that deletion of PAI-1 in adult mice reduces p53, p21, and Bax proteins as well as apoptosis sensitivity in ATII cells but the opposite effects in lung fibroblasts, associated with an attenuation of lung fibrosis after bleomycin challenge. Bleomycin serine (or cysteine) peptidase inhibitor, clade E, member 1 Mus musculus