Title : Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers: potential allies in the COVID-19 pandemic instead of a threat?

Pub. Date : 2021 Apr 30

PMID : 33881142






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In culture of pneumocytes, the captopril/candesartan-induced ACE2 up-regulation was associated with inhibition of ADAM17 activity, counterbalancing increased ACE2 expression, which was associated with reduced SARS-CoV-2 spike protein entry. candesartan ADAM metallopeptidase domain 17 Homo sapiens