Title : Nicotinamide phosphoribosyltransferase inhibitor is a novel therapeutic candidate in LPS-induced neutrophil extracellular traps.

Pub. Date : 2021 Jul

PMID : 33871094






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 LPS and Gram-Negative bacteria induce reactive oxygen species (ROS) -dependent NETs formation via JNK pathway. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens
2 LPS and Gram-Negative bacteria induce reactive oxygen species (ROS) -dependent NETs formation via JNK pathway. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens
3 Additional data indicate that these effects are mediated by suppressing ROS production at least partly via inhibiting JNK activation and depleting NAD(P)H. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens