Pub. Date : 2021 Apr
PMID : 33850935
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nicotine upregulates ACE2 expression and increases competence for SARS-CoV-2 in human pneumocytes. | Nicotine | angiotensin converting enzyme 2 | Homo sapiens |
| 2 | We exposed low angiotensin-converting enzyme 2 (ACE2)-expressing human pulmonary adenocarcinoma A549 epithelial cells to nicotine and assessed ACE2 expression at different times. | Nicotine | angiotensin converting enzyme 2 | Homo sapiens |
| 3 | We exposed low angiotensin-converting enzyme 2 (ACE2)-expressing human pulmonary adenocarcinoma A549 epithelial cells to nicotine and assessed ACE2 expression at different times. | Nicotine | angiotensin converting enzyme 2 | Homo sapiens |
| 4 | Nicotine exposure induces rapid and long-lasting increases in gene and protein expression of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor ACE2, which in turn translates into increased competence for SARS-CoV-2 replication and cytopathic effect. | Nicotine | angiotensin converting enzyme 2 | Homo sapiens |