Title : Pharmacogenomics and Morphine.

Pub. Date : 2021 Sep

PMID : 33847389






1 Functional Relationships(s)
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1 Pharmacokinetically, morphine is primarily metabolized in the liver via glucuronidation by the enzyme uridine diphosphate glucuronosyltransferase family 2-member B7 (UGT2B7) and encounters the transporter proteins organic cation transporter isoform 1 (OCT1) and p-glycoprotein (ABCB1) as it is being distributed throughout the body. Morphine ATP binding cassette subfamily B member 1 Homo sapiens