Title : [Structure and function of a cell-associated complement regulatory protein, membrane cofactor protein (MCP)].

Pub. Date : 1988 Mar

PMID : 3384397






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 This protein migrates Mr 45,000-70,000 dalton region with a broad singlet or doublet on SDS-PAGE, specifically binds to C3b and C4b, has an acidic pI around pH 4, is rich in proline in amino acid analysis, possesses both N-linked and O-linked oligosaccharides, generates iC3b by acting as a cofactor for I-mediated C3b cleavage, and does not disassemble the C3 convertases. Sodium Dodecyl Sulfate complement C3 Homo sapiens
2 This protein migrates Mr 45,000-70,000 dalton region with a broad singlet or doublet on SDS-PAGE, specifically binds to C3b and C4b, has an acidic pI around pH 4, is rich in proline in amino acid analysis, possesses both N-linked and O-linked oligosaccharides, generates iC3b by acting as a cofactor for I-mediated C3b cleavage, and does not disassemble the C3 convertases. Sodium Dodecyl Sulfate complement C3 Homo sapiens