Pub. Date : 2021
PMID : 33842885
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Plasma phosphorylated-tau at threonine-181 detected beta-amyloid-positivity only in the cognitively impaired with a moderate area under curve of 0.67, whereas plasma neurofilament light did not detect beta-amyloid-positivity in either group of participants. | Threonine | microtubule associated protein tau | Homo sapiens |
| 2 | Taken together, these multi-disciplinary results suggest that when combined with clinical information, plasma phosphorylated-tau at threonine-181 and neurofilament light biomarkers, and an MRI-score could effectively identify beta-amyloid+ cognitively unimpaired and impaired (area under curve, 0.80-0.90). | Threonine | microtubule associated protein tau | Homo sapiens |
| 3 | Yet, when the MRI-score is considered in combination with clinical information, plasma phosphorylated-tau at threonine-181 and plasma neurofilament light have minimal added value for detecting beta-amyloid-positivity. | Threonine | microtubule associated protein tau | Homo sapiens |