Title : Eicosapentaenoic and docosahexaenoic acids attenuate methotrexate-induced apoptosis and suppression of splenic T, B-Lymphocytes and macrophages with modulation of expression of CD3, CD20 and CD68.

Pub. Date : 2021 Oct

PMID : 33838352






1 Functional Relationships(s)
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1 EPA and DHA could decrease the MTX-induced increase in the histopathological injury score, splenic hemosiderin, splenic MDA, mRNA expression of TNFalpha, caspase-3 and could increase the MTX-induced decrease in Splenic GSH and mRNA expression for Bcl-2. Eicosapentaenoic Acid tumor necrosis factor Rattus norvegicus