Pub. Date : 2021 Jun 1
PMID : 33831382
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Effects of memantine and its metabolite Mrz 2/373 on soman-induced inhibition of acetylcholinesterase in vitro. | Soman | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
2 | Addition of soman 7.5 nmol/l induced gradual AChE inhibition that became almost complete after 20 min. | Soman | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
3 | It was concluded that it is possible that memantine and Mrz 2/373 can prevent AChE from inhibition by soman, which could, along with known memantine"s neuroprotective activity, explain its potent antidotal effect in soman poisoning. | Soman | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
4 | The potential effect on aging of the soman-AChE complex warrants further studies. | Soman | acetylcholinesterase (Cartwright blood group) | Homo sapiens |