Title : TGF-β2 Promotes Oxidative Stress in Human Trabecular Meshwork Cells by Selectively Enhancing NADPH Oxidase 4 Expression.

Pub. Date : 2021 Apr 1

PMID : 33821883






1 Functional Relationships(s)
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1 Pre-incubating TM cells with GKT137831 attenuated TGF-beta2 mediated increases in intracellular reactive oxygen species (ROS), in COL1A1, COL4A1, and CTGF mRNA expression, in Smad3 protein phosphorylation, in collagens I, collagens IV, and alphaSMA protein expression, and in filamentous actin stress fiber formation. setanaxib SMAD family member 3 Homo sapiens