Pub. Date : 2021 Dec
PMID : 33820450
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Bromodomain-containing protein 4 (BRD4) binds acetylated lysine residues on the N-terminal tails of histones through two bromodomains (BD1 and BD2) to regulate gene transcription. | Lysine | bromodomain containing 4 | Homo sapiens |
| 2 | Bromodomain-containing protein 4 (BRD4) binds acetylated lysine residues on the N-terminal tails of histones through two bromodomains (BD1 and BD2) to regulate gene transcription. | Lysine | bromodomain containing 4 | Homo sapiens |
| 3 | Co-crystal structures show 3",4",7,8-tetrahydroxyflavone binds to the acetylated lysine binding pocket of BRD4-BD1 or BRD4-BD2, but establishes more interactions with BRD4-BD2 than BRD4-BD1. | Lysine | bromodomain containing 4 | Homo sapiens |
| 4 | Co-crystal structures show 3",4",7,8-tetrahydroxyflavone binds to the acetylated lysine binding pocket of BRD4-BD1 or BRD4-BD2, but establishes more interactions with BRD4-BD2 than BRD4-BD1. | Lysine | bromodomain containing 4 | Homo sapiens |