Title : The structure of human dermatan sulfate epimerase 1 emphasizes the importance of C5-epimerization of glucuronic acid in higher organisms.

Pub. Date : 2021 Feb 7

PMID : 33815739






1 Functional Relationships(s)
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1 Based on docking studies and molecular dynamics simulations of the protein structure and a chondroitin substrate, we suggest a novel mechanism of DS-epi1, involving a His/double-Tyr motif. Tyrosine dermatan sulfate epimerase Homo sapiens