Title : Non-ulcerogenic pyrazolyl 2-hydroxychalcones and pyrazolylpyrazolines derived from naturally existing furochromone (khellin): semi-synthesis, docking study and anti-inflammatory activity.

Pub. Date : 2021 Apr 5

PMID : 33813964






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The computational finding supported those of in vitro, where the pyrazolylpyrazolines interacted with the COX-2 enzyme in a similar orientation to that of Celecoxib, while chlacones were found to exhibit similar orientation to that of Diclofenac. Diclofenac mitochondrially encoded cytochrome c oxidase II Homo sapiens