Title : Integrin αvβ3 Engagement Regulates Glucose Metabolism and Migration through Focal Adhesion Kinase (FAK) and Protein Arginine Methyltransferase 5 (PRMT5) in Glioblastoma Cells.

Pub. Date : 2021 Mar 5

PMID : 33807786






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Integrin alphavbeta3 engagement with osteopontin promotes glucose uptake and aerobic glycolysis, while inhibiting mitochondrial oxidative phosphorylation. Glucose integrin subunit alpha V Homo sapiens
2 Blocking or downregulation of integrin alphavbeta3 inhibits glucose uptake and aerobic glycolysis and promotes mitochondrial oxidative phosphorylation, resulting in decreased migration and growth in glioblastoma cells. Glucose integrin subunit alpha V Homo sapiens