Title : Physiologically Based Pharmacokinetic Modeling of Bupropion and Its Metabolites in a CYP2B6 Drug-Drug-Gene Interaction Network.

Pub. Date : 2021 Mar 4

PMID : 33806634






1 Functional Relationships(s)
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1 DDI model performance was evaluated by prediction of clinical studies with rifampicin (CYP2B6 and CYP2C19 inducer), fluvoxamine (CYP2C19 inhibitor) and voriconazole (CYP2B6 and CYP2C19 inhibitor). Rifampin cytochrome P450 family 2 subfamily B member 6 Homo sapiens