Title : Nicotinamide Treatment Facilitates Mitochondrial Fission through Drp1 Activation Mediated by SIRT1-Induced Changes in Cellular Levels of cAMP and Ca2.

Pub. Date : 2021 Mar 10

PMID : 33802063






1 Functional Relationships(s)
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1 These results suggest that NAD+-mediated SIRT1 activation facilitates mitochondrial fission through activation of Drp1 by suppressing its phosphorylation and accelerating its dephosphorylation. NAD sirtuin 1 Homo sapiens