Title : Oxoglaucine mediates Ca2+ influx and activates autophagy to alleviate osteoarthritis through the TRPV5/calmodulin/CAMK-II pathway.

Pub. Date : 2021 Aug

PMID : 33786819






1 Functional Relationships(s)
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1 KEY RESULTS: Oxoglaucine suppressed the expression of pro-inflammatory and apoptosis-related cytokines, such as TNF-alpha, IL-6, IL-1beta, MMP-13, CASP-3, BAX, and prevented matrix degradation in OA chondrocytes. oxoglaucine interleukin 1 alpha Homo sapiens