Title : Discovery and characterization of small-molecule inhibitors of NLRP3 and NLRC4 inflammasomes.

Pub. Date : 2021 Jan-Jun

PMID : 33781745






1 Functional Relationships(s)
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1 Previous work has demonstrated that inhibiting the ATPase activity of the Nucleotide-Binding Oligomerization Domain, Leucine-Rich Repeat and Pyrin Domain (NLR) containing protein 3 (NLRP3) disrupts inflammasome assembly and function. Leucine NLR family pyrin domain containing 3 Homo sapiens