Title : Power of an Organic Electron Acceptor in Modulation of Intracellular Mitochondrial Reactive Oxygen Species: Inducing JNK- and Caspase-Dependent Apoptosis of Cancer Cells.

Pub. Date : 2021 Mar 23

PMID : 33778293






2 Functional Relationships(s)
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1 Power of an Organic Electron Acceptor in Modulation of Intracellular Mitochondrial Reactive Oxygen Species: Inducing JNK- and Caspase-Dependent Apoptosis of Cancer Cells. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens
2 This effect of BBT in ROS generation activates JNK and p38 stress-dependent pathways and resulted in mitochondrial-dependent apoptotic cell death with the reduction in expression of several important cyto-protecting factors (Hsp27 and NFkappaB), indicating its potential in inhibition of cancer cell relapse. Reactive Oxygen Species mitogen-activated protein kinase 8 Homo sapiens