Title : Impact of high glucose levels and glucose lowering on risk of ischaemic stroke: a Mendelian randomisation study and meta-analysis.

Pub. Date : 2021 Jul

PMID : 33765180






1 Functional Relationships(s)
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1 In meta-analyses of glucose-lowering drugs, the risk ratio for stroke was 0.85 (0.77, 0.94) for glucagon-like peptide-1 receptor agonists and 0.82 (0.69, 0.98) for thiazolidinediones, while sulfonylureas, dipeptidyl peptidase-4 inhibitors, sodium-glucose cotransporter 2 inhibitors, alpha-glucosidase inhibitors, meglitinides and metformin individually lacked statistical evidence of an effect on stroke risk. Glucose dipeptidyl peptidase 4 Homo sapiens