Title : Structural insights into the lipid and ligand regulation of serotonin receptors.

Pub. Date : 2021 Apr

PMID : 33762731






1 Functional Relationships(s)
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1 Here we report five structures of 5-HT receptor-G-protein complexes: 5-HT1A in the apo state, bound to 5-HT or bound to the antipsychotic drug aripiprazole; 5-HT1D bound to 5-HT; and 5-HT1E in complex with a 5-HT1E- and 5-HT1F-selective agonist, BRL-54443. Serotonin 5-hydroxytryptamine receptor 1A Homo sapiens