Pub. Date : 2021 May
PMID : 33761605
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Heme oxygenase-1 inducer hemin does not inhibit SARS-CoV-2 virus infection. | Hemin | heme oxygenase 1 | Homo sapiens |
| 2 | Given that hemin is a natural inducer of the HO-1 gene, the aim of this study was to develop an in vitro assay to analyze the antiviral potency of hemin against SARS-CoV-2 infection. | Hemin | heme oxygenase 1 | Homo sapiens |
| 3 | Given that hemin is a natural inducer of the HO-1 gene, the aim of this study was to develop an in vitro assay to analyze the antiviral potency of hemin against SARS-CoV-2 infection. | Hemin | heme oxygenase 1 | Homo sapiens |
| 4 | Hemin administration to the culture medium induced a high induction in the expression of the HO-1 gene that was stronger in Vero-E6 macaque-derived cells than in the human Calu-3 cell line. | Hemin | heme oxygenase 1 | Homo sapiens |
| 5 | In conclusion, although exposure to hemin induced strong HO-1 up-regulation, this effect was unable to inhibit or delay the progression of SARS-CoV-2 infection in two epithelial cell lines susceptible to infection. | Hemin | heme oxygenase 1 | Homo sapiens |