Title : Requirement of hormone for thermal conversion of the glucocorticoid receptor to a DNA-binding state.

Pub. Date : 1988 Jun 16

PMID : 3374615






1 Functional Relationships(s)
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1 Here we show that under conditions permitting minimal in vitro manipulation, the steroid-free glucocorticoid receptor in crude cytosol associates with the hsp90 heat shock protein (relative molecular mass Mr approximately equal to 90,000) to form a large 300K complex, rather than the 94K liganded receptor monomer. Steroids nuclear receptor subfamily 3 group C member 1 Homo sapiens