Pub. Date : 2021 May
PMID : 33741398
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | An intronic DHCR7 genetic polymorphism associates with vitamin D serum level and incidence of acute coronary syndrome. | Vitamin D | 7-dehydrocholesterol reductase | Homo sapiens |
| 2 | AIM: This study aims to correlate two polymorphisms in the DHCR7/NADSYN1 genetic locus with levels of circulatory vitamin D and the presentation of ACS in an Egyptian population. | Vitamin D | 7-dehydrocholesterol reductase | Homo sapiens |
| 3 | Allele A of the DHCR7 polymorphism was found to correlate with serum vitamin D deficiency and incidence of ACS classes: NSTEMI, STEMI and unstable angina, when compared to allele G. On the other hand, the NADSYN1 polymorphism rs2276360 correlated with serum 25(OH)D3 deficiency. | Vitamin D | 7-dehydrocholesterol reductase | Homo sapiens |
| 4 | CONCLUSION: We conclude that rs11606033, which is an intronic SNP between exon 4 and exon 5 of the DHCR7 gene, influences vitamin D serum abundance and more importantly ACS incidence. | Vitamin D | 7-dehydrocholesterol reductase | Homo sapiens |