Title : A novel flavonoid from Fissistigma cupreonitens, 5‑hydroxy‑7,8‑dimethoxyflavanone, competitively inhibited the efflux function of human P-glycoprotein and reversed cancer multi-drug resistance.

Pub. Date : 2021 May

PMID : 33735724






1 Functional Relationships(s)
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1 The docking results showed that 5-hydroxy-7,8-dimethoxyflavanone and verapamil exhibited similar binding affinity to P-gp. Verapamil ATP binding cassette subfamily B member 1 Homo sapiens