Title : The ALK inhibitors, alectinib and ceritinib, induce ALK-independent and STAT3-dependent glioblastoma cell death.

Pub. Date : 2021 Jun

PMID : 33728771






1 Functional Relationships(s)
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1 In addition, treatment with either alectinib or ceritinib modulated the activation of various molecules downstream of RTK signaling and induced caspase-dependent/independent cell death mainly by inhibiting signal transducer and activator of transcription 3 activation in human GBM cells. alectinib ret proto-oncogene Homo sapiens