Title : Cytochrome P-450-catalyzed dehydrogenation of 1,4-dihydropyridines.

Pub. Date : 1988 Jun 15

PMID : 3372517






1 Functional Relationships(s)
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1 A variety of different 4-substituted 1,4-dihydropyridine Hantzsch esters are substrates for ring dehydrogenation by a cytochrome P-450 (P-450) enzyme (P-450 UT-A); the substitutent could be varied from a hydrogen to a naphthalenyl, but a pyrenyl derivative was not dehydrogenated. Hydrogen cytochrome P450 family 4 subfamily F member 3 Homo sapiens