Pub. Date : 2021 Apr
PMID : 33714595
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | On the basis of our review of the published literature, we speculate that several unifying cutaneous and systemic mechanisms may explain COVID-19-associated pernio: (1) SARS-CoV-2 cell infection occurs through the cellular receptor angiotensin-converting enzyme 2 mediated by transmembrane protease serine 2, subsequently affecting the renin-angiotensin-aldosterone system with an increase in the vasoconstricting, pro-inflammatory, and prothrombotic angiotensin II pathway. | Aldosterone | angiotensin converting enzyme 2 | Homo sapiens |