Title : Huperzine A lowers intraocular pressure via the M3 mAChR and provides retinal neuroprotection via the M1 mAChR: a promising agent for the treatment of glaucoma.

Pub. Date : 2021 Feb

PMID : 33708959






1 Functional Relationships(s)
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1 The effects were abolished by atropine and the selective M1 mAChR antagonist pirenzepine in OGD-induced PRNs suggesting an indirect M1 mAChR-mediated effect via inhibiting AChE activity to increase endogenous ACh level. Atropine acetylcholinesterase (Cartwright blood group) Homo sapiens