Title : Physiologically-based pharmacokinetic modeling to predict drug interactions of lemborexant with CYP3A inhibitors.

Pub. Date : 2021 May

PMID : 33704920






1 Functional Relationships(s)
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1 The model further predicted that DDI effects of weak CYP3A inhibitors (fluoxetine and ranitidine) are weak, and effects of moderate inhibitors (erythromycin and verapamil) are moderate. Ranitidine cytochrome P450 family 3 subfamily A member 4 Homo sapiens