Title : Heterogeneous NLRP3 inflammasome signature in circulating myeloid cells as a biomarker of COVID-19 severity.

Pub. Date : 2021 Mar 9

PMID : 33683342






2 Functional Relationships(s)
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Protein Name
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1 Unexpectedly, the CD66b+CD16dim granulocytes had decreased nigericin-triggered caspase-1 activation potential associated with an increased percentage of NLRP3 inflammasome impaired immature neutrophils and a loss of eosinophils in the blood. Nigericin CEA cell adhesion molecule 8 Homo sapiens
2 In patients who recovered from COVID-19, nigericin-triggered caspase-1 activation potential in CD66b+CD16dim cells was restored and the proportion of immature neutrophils was similar to control. Nigericin CEA cell adhesion molecule 8 Homo sapiens