Title : Total glucosides of paeony protects THP-1 macrophages against monosodium urate-induced inflammation via MALAT1/miR-876-5p/NLRP3 signaling cascade in gouty arthritis.

Pub. Date : 2021 Jun

PMID : 33677310






4 Functional Relationships(s)
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Protein Name
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1 Total glucosides of paeony protects THP-1 macrophages against monosodium urate-induced inflammation via MALAT1/miR-876-5p/NLRP3 signaling cascade in gouty arthritis. Uric Acid NLR family pyrin domain containing 3 Homo sapiens
2 Overexpression of NLRP3 or MALAT1 reversed the protective effects of TGP in MSU-induced THP-1 macrophages. Uric Acid NLR family pyrin domain containing 3 Homo sapiens
3 TGP suppressed MSU-induced inflammation in THP-1 macrophages through regulating MALAT1/miR-876-5p/NLRP3 axis. Uric Acid NLR family pyrin domain containing 3 Homo sapiens
4 TGP suppressed MSU-induced activation of TLR4/MyD88/NF-kappaB pathway through regulating MALAT1/miR-876-5p/NLRP3 axis. Uric Acid NLR family pyrin domain containing 3 Homo sapiens