Title : Demystifying Excess Immune Response in COVID-19 to Reposition an Orphan Drug for Down-Regulation of NF-κB: A Systematic Review.

Pub. Date : 2021 Feb 27

PMID : 33673529






2 Functional Relationships(s)
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1 Neutralization of upstream histamine by histamine-conjugated normal human immunoglobulin has been demonstrated to inhibit the nuclear translocation of NF-kappaB, thereby preventing the release of pro-inflammatory cytokines Interleukin (IL) 1beta, TNF-alpha, and IL-6 and IL-10 in a safer manner. Histamine interleukin 6 Homo sapiens
2 Neutralization of upstream histamine by histamine-conjugated normal human immunoglobulin has been demonstrated to inhibit the nuclear translocation of NF-kappaB, thereby preventing the release of pro-inflammatory cytokines Interleukin (IL) 1beta, TNF-alpha, and IL-6 and IL-10 in a safer manner. Histamine interleukin 6 Homo sapiens