Title : Losartan Improves Memory, Neurogenesis and Cell Motility in Transgenic Alzheimer's Mice.

Pub. Date : 2021 Feb 20

PMID : 33672482






2 Functional Relationships(s)
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1 Consistent with our previous results with intranasal losartan, repeated intraperitoneal administration (10 mg/kg) resulted in a remarkable decrease in Abeta plaques and soluble Abeta42, as well as inflammatory cytokines (IL-2, IL-6 and TNFalpha). Losartan amyloid beta (A4) precursor protein Mus musculus
2 The improvement of cell motility of Abeta-affected astrocytes by losartan deserves further in vivo investigation, which may lead to new strategies for AD treatment. Losartan amyloid beta (A4) precursor protein Mus musculus