Title : The Role of Central Serotonin Neurons and 5-HT Heteroreceptor Complexes in the Pathophysiology of Depression: A Historical Perspective and Future Prospects.

Pub. Date : 2021 Feb 15

PMID : 33672070






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 For instance, a disruption and/or dysfunction in the 5-HT1A-FGFR1 heteroreceptor complexes in the raphe-hippocampal serotonin neuron systems can contribute to the development of MD. Serotonin 5-hydroxytryptamine receptor 1A Homo sapiens
2 Reduced 5-HT1A auto-receptor function, increased plasticity and trophic activity in the midbrain raphe 5-HT neurons can develop via agonist activation of allosteric receptor-receptor interactions in the 5-HT1A-FGFR1 heterocomplex. Serotonin 5-hydroxytryptamine receptor 1A Homo sapiens