Title : Design, Synthesis, and Biological Evaluation of a Series of 5- and 7-Hydroxycoumarin Derivatives as 5-HT1A Serotonin Receptor Antagonists.

Pub. Date : 2021 Feb 24

PMID : 33668396






1 Functional Relationships(s)
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1 We have designed and synthesized a series of 60 new 5- and 7-hydroxycoumarin derivatives bearing the piperazine moiety with the expected binding to 5-HT1A and 5-HT2A receptors. Piperazine 5-hydroxytryptamine receptor 1A Homo sapiens