Pub. Date : 2020
PMID : 33658919
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Apigenin Attenuates Acetaminophen-Induced Hepatotoxicity by Activating AMP-Activated Protein Kinase/Carnitine Palmitoyltransferase I Pathway. | Acetaminophen | protein kinase AMP-activated non-catalytic subunit beta 1 | Homo sapiens |
2 | In summary, the study demonstrates that API attenuates APAP-induced hepatotoxicity by activating the AMPK/GSK-3beta signaling pathway, which subsequently promotes CPT1A activity and activates the NRF2 antioxidant pathway. | Acetaminophen | protein kinase AMP-activated non-catalytic subunit beta 1 | Homo sapiens |