Title : Apigenin Attenuates Acetaminophen-Induced Hepatotoxicity by Activating AMP-Activated Protein Kinase/Carnitine Palmitoyltransferase I Pathway.

Pub. Date : 2020

PMID : 33658919






2 Functional Relationships(s)
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1 Apigenin Attenuates Acetaminophen-Induced Hepatotoxicity by Activating AMP-Activated Protein Kinase/Carnitine Palmitoyltransferase I Pathway. Acetaminophen protein kinase AMP-activated non-catalytic subunit beta 1 Homo sapiens
2 In summary, the study demonstrates that API attenuates APAP-induced hepatotoxicity by activating the AMPK/GSK-3beta signaling pathway, which subsequently promotes CPT1A activity and activates the NRF2 antioxidant pathway. Acetaminophen protein kinase AMP-activated non-catalytic subunit beta 1 Homo sapiens