Title : An Active Site Inhibitor Induces Conformational Penalties for ACE2 Recognition by the Spike Protein of SARS-CoV-2.

Pub. Date : 2021 Mar 18

PMID : 33657325






1 Functional Relationships(s)
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Protein Name
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1 This weakening of binding strength was observed to be due to the destabilization of the interactions between ACE2 residues Glu-35, Glu-37, Tyr-83, Lys-353, and Arg-393 and the SARS-CoV-2 s-protein receptor binding domain (RBD). Arginine angiotensin converting enzyme 2 Homo sapiens