Title : Mechanism and Inhibition of Human Methionine Adenosyltransferase 2A.

Pub. Date : 2021 Mar 16

PMID : 33656855






1 Functional Relationships(s)
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1 Here we show that MAT2A has a sequential mechanism with a rate-limiting step of formation of AdoMet, followed by rapid hydrolysis of the beta-gamma bond of triphosphate, and rapid release of phosphate and pyrophosphate. diphosphoric acid methionine adenosyltransferase 2A Homo sapiens