Title : Investigating the influence of relevant pharmacogenetic variants on the pharmacokinetics and pharmacodynamics of orally administered docetaxel combined with ritonavir.

Pub. Date : 2021 Jun

PMID : 33649517






1 Functional Relationships(s)
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1 In this study, we aimed to assess the functional significance of 14 polymorphisms in the CYP3A, CYP1B1, ABCB1, ABCC2, and SLCO1B3 genes for the pharmacokinetics and pharmacodynamics of oral docetaxel, co-administered with ritonavir. Ritonavir cytochrome P450 family 3 subfamily A member 4 Homo sapiens