Title : Development of antitumor biguanides targeting energy metabolism and stress responses in the tumor microenvironment.

Pub. Date : 2021 Mar 1

PMID : 33649449






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Additionally, the protein expression of HIF-1alpha induced by hypoxia and of GRP78 and GRP94 induced by glucose starvation was markedly suppressed by the biguanides, thereby inhibiting angiogenesis. Biguanides hypoxia inducible factor 1 subunit alpha Homo sapiens