Title : Genome wide association study of HTLV-1-associated myelopathy/tropical spastic paraparesis in the Japanese population.

Pub. Date : 2021 Mar 16

PMID : 33649182






2 Functional Relationships(s)
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1 Logistic regression analysis identified amino acid position 7 in the G-BETA domain of HLA-DRB1 as strongly associated with HAM/TSP (P = 9.52 x 10-10); individuals homozygous for leucine had an associated increased risk of HAM/TSP (odds ratio, 9.57), and proline was protective (odds ratio, 0.65). Leucine thrombospondin 1 Homo sapiens
2 Logistic regression analysis identified amino acid position 7 in the G-BETA domain of HLA-DRB1 as strongly associated with HAM/TSP (P = 9.52 x 10-10); individuals homozygous for leucine had an associated increased risk of HAM/TSP (odds ratio, 9.57), and proline was protective (odds ratio, 0.65). Leucine thrombospondin 1 Homo sapiens