Pub. Date : 2021 Mar
PMID : 33647767
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Testosterone was higher in subjects with AR long-polyQ, possibly indicating receptor resistance (p = 0.042 Mann-Whitney U test). | Testosterone | androgen receptor | Homo sapiens |
2 | Failure of the endocrine feedback to overcome AR signaling defects by increasing testosterone levels during the infection leads to the polyQ tract becoming dominant to serum testosterone levels for the clinical outcome. | Testosterone | androgen receptor | Homo sapiens |
3 | Failure of the endocrine feedback to overcome AR signaling defects by increasing testosterone levels during the infection leads to the polyQ tract becoming dominant to serum testosterone levels for the clinical outcome. | Testosterone | androgen receptor | Homo sapiens |
4 | These results may contribute to designing reliable clinical and public health measures and provide a rationale to test testosterone as adjuvant therapy in men with COVID-19 expressing long AR polyQ repeats. | Testosterone | androgen receptor | Homo sapiens |