Title : East to West not North-West: Structure-Based Mechanistic Resolution of 8-Hydroxyl Replacement and Resulting Effects on the Activities of Imidazole-Based Heme Oxygenase-1 Inhibitors.

Pub. Date : 2021 Apr

PMID : 33646477






1 Functional Relationships(s)
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1 In a recent study, two selective azole-based HO-1 inhibitors (Cpd1 and Cpd2) were synthesized, which exhibited differential inhibitory potencies of ~200mum. Azoles heme oxygenase 1 Homo sapiens