Pub. Date : 2021 Feb 27
PMID : 33640015
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To identify the necessary cell signaling proteins in E2-induced TGFbeta1 and TGFbeta2 transcription, human dermal fibroblasts were pre-treated with an inhibitor of the extracellular signal-regulated kinase/mitogen-activated protein kinase (ERK/MAPK) pathway, U0126. | Estradiol | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | Additionally, inhibiting E2-induced ERK/MAPK activation and early growth response 1 (EGR1) transcription prevents the E2-induced increase in TGFbeta1 and TGFbeta2 transcription and translation. | Estradiol | mitogen-activated protein kinase 1 | Homo sapiens |
| 3 | Additionally, inhibiting E2-induced ERK/MAPK activation and early growth response 1 (EGR1) transcription prevents the E2-induced increase in TGFbeta1 and TGFbeta2 transcription and translation. | Estradiol | mitogen-activated protein kinase 1 | Homo sapiens |