Title : Role of myeloperoxidase-derived oxidants in the induction of vascular smooth muscle cell damage.

Pub. Date : 2021 Apr

PMID : 33631301






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Myeloperoxidase (MPO) is released by activated immune cells and forms the oxidants hypochlorous acid (HOCl) and hypothiocyanous acid (HOSCN) from the competing substrates chloride and thiocyanate. thiocyanate myeloperoxidase Homo sapiens
2 Myeloperoxidase (MPO) is released by activated immune cells and forms the oxidants hypochlorous acid (HOCl) and hypothiocyanous acid (HOSCN) from the competing substrates chloride and thiocyanate. thiocyanate myeloperoxidase Homo sapiens
3 Overall, these data provide new insight into pathways promoting vascular dysfunction during chronic inflammation, support the use of thiocyanate as a means to modulate MPO-induced cellular damage in atherosclerosis. thiocyanate myeloperoxidase Homo sapiens