Title : Evaluation of a human iPSC-derived BBB model for repeated dose toxicity testing with cyclosporine A as model compound.

Pub. Date : 2021 Jun

PMID : 33631201






1 Functional Relationships(s)
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1 Although BLECs were still undergoing transcriptional changes over time, a targeted transcriptome analysis (TempO-Seq) indicated a time and concentration dependent activation of ATF4, XBP1, Nrf2 and p53 stress response pathways under CsA treatment. Cyclosporine NFE2 like bZIP transcription factor 2 Homo sapiens