Title : Using the CYP3A Activity Evaluation to Predict the Efficacy and Safety of Diazepam in Patients With Alcohol Withdrawal Syndrome.

Pub. Date : 2021 Feb 24

PMID : 33622083






2 Functional Relationships(s)
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1 CONCLUSION: Possible relationship between the CYP3A activity, evaluated by the content of the urinary endogenous substrate of the given isoenzyme and its metabolite, the 6-beta-hydroxy cortisol (6-beta-HC) / cortisol ratio, and the efficacy of diazepam was demonstrated. 6 beta-hydroxycortisol cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 CONCLUSION: Possible relationship between the CYP3A activity, evaluated by the content of the urinary endogenous substrate of the given isoenzyme and its metabolite, the 6-beta-hydroxy cortisol (6-beta-HC) / cortisol ratio, and the efficacy of diazepam was demonstrated. 6 beta-hydroxycortisol cytochrome P450 family 3 subfamily A member 4 Homo sapiens