Title : Assessment of azithromycin as an anticancer agent for treatment of imatinib sensitive and resistant CML cells.

Pub. Date : 2021 Mar

PMID : 33607534






2 Functional Relationships(s)
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1 Furthermore, AZT and AZT/IMA combination decreased Pgp function in K562R cells in comparison with their controls. Imatinib Mesylate ATP binding cassette subfamily B member 1 Homo sapiens
2 One of the mechanisms underlying the potent anticancer effect of combined AZT/IMA could be its ability to inhibit Pgp function and increase intracellular accumulation of IMA which leads to the induction of apoptosis in K562R cells. Imatinib Mesylate ATP binding cassette subfamily B member 1 Homo sapiens